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Air cleanliness 100, 10 000 and 100 000 air purification treatment should be used at the beginning, in effect, high efficiency filter three filters. For the 300,000 air purification, can be used instead of sub-efficient filter efficiency filter.
■ Air filter selection, arrangement should meet the following requirements:
⑴ efficiency air filter should be focused on setting a positive pressure in the purge air conditioning segment;
⑵ efficient or sub-efficiency air filters should be set at the end of the clean air conditioning systems;
⑶ in effect, high efficiency air filter should be smaller than or equal to the rated air flow selection.
■ for larger, higher air cleanliness, location, focus and silencer, vibration control demanding clean room (area) should adopt a centralized air conditioning system. On the other hand, can be distributed air conditioning system.
■ air purification system following conditions should be provided separately:
⑴ unidirectional flow clean room and non-unidirectional flow clean room (area)
⑵ efficient air purification system efficiency air purification systems;
⑶ run time shifts or different clean room (area).
■ following the production of air purification system should be set up independently, should be separated by a certain distance between its exhaust port and inlet air purification system of other drugs.
⑴ strong sensitizing drugs such as penicillin;
⑵ β- lactam structure drugs;
⑶ hormone drugs;
⑷ anti-tumor drugs;
⑸ virulent bacterium Bacillus microorganisms and products;
⑹ radiopharmaceuticals;
⑺ have bacteria (viruses) operating area.
■ Air air purification system of the following circumstances, such as treated can not avoid cross-contamination, it should not be recycled.
⑴ pulverized solid material, weighing, mixing, feed system, tableting, coating, filling and other processes;
⑵ solid oral granule formulation, finished drying equipment used in clean air;
⑶ APIs refined organic solvent refining, drying process;
⑷ pathogens operating area;
⑸ radiopharmaceuticals production area;
⑹ the process produces large amounts of harmful substances, volatile gas production processes.